Post-marketing surveillance study on the preventive potential of hempseed oil for Capecitabin-induced Hand-Foot Syndrome
Hand-Foot Syndrome (HFS) is an erythematic skin reaction on the palms of the hands and/or soles of the feet. It occurs as a side effect of cytostatic chemotherapy, particularly when Capecitabin is used. Depending on the severity of the skin lesions, patients suffer mild to very severe difficulties in everyday life. To date, therapy options are limited by the large number of unknown factors in the pathogenesis of HFS. In severe cases, patients may have to pause their chemotherapy, reduce dosage, or discontinue their treatment. The use of hempseed oil (orally/systemically and topically) appears to be a new and promising avenue for preventive treatment. Its preventive potential was examined in a post-marketing surveillance study with 17 patients.