Actas Urol Esp. 2015 Mar;39(2):112-117. doi: 10.1016/j.acuro.2014.07.003. Epub 2014 Sep 7.

American cranberry (proanthocyanidin 120mg): Its value for the prevention of urinary tracts infections after ureteral catheter placement.

Barnoiu OS1, Sequeira-García Del Moral J2, Sanchez-Martínez N2, Díaz-Molina P2, Flores-Sirvent L2, Baena-González V2.



Urinary tract infection (UTI) is among the most frequent complications after urinary tract surgical procedures, mainly when catheter placement is necessary. Although the use of American cranberry has been related with a reduced risk of UTI, there is no study reporting the value of its prevention effect against catheter-associated urinary tract infections.


A prospective trial comparing UTI rate (positive urine culture) among 31 patients with double J catheter (JJ) and adding American cranberry (120mg) in routine prophylactic therapy, and 31 patients with JJ catheter only receiving routine prophylactic therapy.


Regarding general characteristics of the populations no significant difference among groups have been found. Only significant differences have been observed when the variables “cranberry treatment” and “dwell time of JJ catheter” were related. “Dwell time of JJ catheter” was higher in patients with UTI (35.9 compared 28.5 days [P=.03]). UTI percentage was lower in cranberry supplemented patient group (12.9 compared to 38.7% [P=.04]).


We can conclude that American cranberry (120mg) has an adjuvant effect in the prevention of UTI in patients with JJ catheter after surgery.